PREVALENCE OF RENAL ARTERY STENOSIS IN HYPERTENSIVE PATIENTS UNDERGOING CORONARY ANGIOGRAPHY

Abstract

Abstract
INTRODUCTION: Atherosclerotic renal artery stenosis (RAS) is an important cause of
secondary hypertension as well as ischemic nephropathy. Little information is available
about the incidence of RAS in hypertensive patients in the Iranian society. This study was
performed to determine the prevalence of RAS and its related risk factors in hypertensive
patients.
METHODS: A cross-sectional study was conducted on 122 hypertensive patients (80
males and 42 females) aged 33-74 years (mean age: 54±8.5 years), all of whom
underwent coronary angiography and selective renal angiography.
RESULTS: According to angiographic data, 95 patients (77.9%) had coronary artery
disease (CAD) and 27 (22.1%) had normal coronary arteries. RAS was seen in 22 patients
(23.1%) with CAD and hypertension, and in 4 patients (14.8%) with hypertension and
normal coronary arteries. Overall, 26 patients (21.3%) had RAS, which was classified as
significant (14.7%) and non-significant (6.6%). RAS significantly correlated to the female
gender (P=0.019), age (P=0.002), diabetes mellitus (P=0.025) and severity of
hypertension (P=0.006).
CONCLUSIONS: The prevalence of significant RAS among hypertensive patients
undergoing coronary angiography was 14.7%. Factors like old age, severe hypertension,
diabetes mellitus and female gender were clinical predictors of RAS.
Key Words: Hypertension, renal artery stenosis, coronary artery disease, coronary
artery angiography.