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Fall 2005 |
A STUDY OF THE EFFECT OF LIPOSUCTION ON CORONARY DISEASE RISK FACTORS, INFLAMMATORY MARKERS, AND LEFT VENTRICULAR MASS IN NON-DIABETIC OBESE WOMEN
Abstract
Abstract
INTRODUCTION: Liposuction is a surgical procedure effective in reducing body fat, with
growing application in conjunction with diet and exercise therapy in the treatment of obesity.
In view of the positive effect of weight reduction on cardiovascular disease (CVD) risk
factors, such as body mass index (BMI), waist circumference (WC), waist-to-hip ratio
(WHR), systolic and diastolic pressure, lipid profile, fasting blood sugar, insulin resistance,
inflammatory markers (e.g. chronic reactive protein: CRP), antioxidant capacity, fibrinogen
and lipoprotein A (Lpa), this study was conducted to assess the effect of liposuction as a
therapeutic procedure in the treatment of obesity.
METHODS: A total of 24 non-diabetic obese women (BMI>30) with a mean age of
48.7±7.3 years were studied. Before liposuction, the subjects filled out questionnaires
obtaining demographic information. Complete physical examination, measurement of waist
and hip circumference, height, weight and calculation of WHR and BMI were performed.
Fasting blood samples were taken to measure fasting blood glucose, total cholesterol, highdensity
lipoprotein (HDL), low-density lipoprotein (LDL), triglyceride (TG), fibrinogen,
antioxidant capacity, CRP, lipoprotein A, serum insulin, and insulin resistance. All
measurements and physical examinations were repeated 12-14 weeks after liposuction.
Data were analyzed with SPSS11 software using paired t-test and repeated measure
ANOVA.
RESULTS: WHR, BMI and LDL decreased significantly following liposuction (P<0.05).
Other parameters, however, did not change significantly, although there were signs of
positive changes.
DISCUSSION: Liposuction decreases BMI, WHR and LDL within 12-14 weeks of
liposuction. Providing these reductions are maintained, liposuction may prove valuable in
reducing CVD risk factors, besides offering a means for obesity control.
Keywords • Liposuction • Obesity
INTRODUCTION: Liposuction is a surgical procedure effective in reducing body fat, with
growing application in conjunction with diet and exercise therapy in the treatment of obesity.
In view of the positive effect of weight reduction on cardiovascular disease (CVD) risk
factors, such as body mass index (BMI), waist circumference (WC), waist-to-hip ratio
(WHR), systolic and diastolic pressure, lipid profile, fasting blood sugar, insulin resistance,
inflammatory markers (e.g. chronic reactive protein: CRP), antioxidant capacity, fibrinogen
and lipoprotein A (Lpa), this study was conducted to assess the effect of liposuction as a
therapeutic procedure in the treatment of obesity.
METHODS: A total of 24 non-diabetic obese women (BMI>30) with a mean age of
48.7±7.3 years were studied. Before liposuction, the subjects filled out questionnaires
obtaining demographic information. Complete physical examination, measurement of waist
and hip circumference, height, weight and calculation of WHR and BMI were performed.
Fasting blood samples were taken to measure fasting blood glucose, total cholesterol, highdensity
lipoprotein (HDL), low-density lipoprotein (LDL), triglyceride (TG), fibrinogen,
antioxidant capacity, CRP, lipoprotein A, serum insulin, and insulin resistance. All
measurements and physical examinations were repeated 12-14 weeks after liposuction.
Data were analyzed with SPSS11 software using paired t-test and repeated measure
ANOVA.
RESULTS: WHR, BMI and LDL decreased significantly following liposuction (P<0.05).
Other parameters, however, did not change significantly, although there were signs of
positive changes.
DISCUSSION: Liposuction decreases BMI, WHR and LDL within 12-14 weeks of
liposuction. Providing these reductions are maintained, liposuction may prove valuable in
reducing CVD risk factors, besides offering a means for obesity control.
Keywords • Liposuction • Obesity
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