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Spring 2011:1-6 |
Estimation of left ventricular end diastolic pressure (LVEDP) in patients with ischemic heart disease by echocardiography and compare it with the results of cardiac catheterization
Abstract
BACKGROUND: Doppler echocardiography has been proposed as an appropriate non-invasive
assay to estimate left ventricular end diastolic pressure (LVEDP). The aim of present research
was to estimate the LVEDP in patients with ischemic heart disease by echocardiography and
compare it with the results of cardiac catheterisation and to determine the effect of different
echocardiographic variables on its measurement.
METHODS: In this descriptive-analytic study, patients with diagnosed ischemic heart disease
were selected by nonrandomized sampling method. Selected population underwent M-mode
and pulse doppler echocardiographic evaluation and parameters such as Q-Mitral valve E
(Q-MVE), Q-Aortic valve closure (Q-AVC), Aortic valve closure-E (AVC-E), Q-Mitral valve
closure/Aortic valve closure-E (Q-MVC/AVC-E), left ventricle-deceleration time (LV-DT), peak
velocity-deceleration time (PV-DT) and A/E velocity time integral (A/E VTI) were evaluated.
Immediately after echocardiography all patients underwent left heart catheterization for LVEDP
measurement. The relation between different echocardiographic measurements and LVEDP,
obtained by cardiac catheterization, was evaluated.
RESULTS: In this study, 47 patients with ischemic heart disease with mean age (±SD) of
53 ± 13 were studied. There was a significant correlation between LVDEP and A/E VTI (r=0.44,
P = 0.001, and also between LVEDP and PV-DT in patients with A/E VTI ≥1.1(r = -0.58, P = 0.02).
There was a significant correlation between LVEDP and Q-MVC/AVC-E in patients with LVEDP
>18mmHg (r = 0.76, P= 0.03) and those with LVEDP ≤18 mmHg and A/E VTI < 1.1
(r = 0.37, P= 0.03). The correlation between LVEDP and A/E VTI was more significant in men,
in patients aged > 50 years with EF > 55%, without LVH, without MR and those with coronary
artery disease (P < 0.05).
CONCLUSION: Some echocardiographic indices such as A/E VTI, Q-MVC/AVC-E and PV-DT
are able to measure LVEDP especially in male patients aged > 50 years, without LVH, without
MR and those with coronary artery disease but it is necessary to determine specific conditions
and factors affecting these indices, by further studies.
Keywords: LVEDP, Coronary Artery Disease, Echocardiography.
assay to estimate left ventricular end diastolic pressure (LVEDP). The aim of present research
was to estimate the LVEDP in patients with ischemic heart disease by echocardiography and
compare it with the results of cardiac catheterisation and to determine the effect of different
echocardiographic variables on its measurement.
METHODS: In this descriptive-analytic study, patients with diagnosed ischemic heart disease
were selected by nonrandomized sampling method. Selected population underwent M-mode
and pulse doppler echocardiographic evaluation and parameters such as Q-Mitral valve E
(Q-MVE), Q-Aortic valve closure (Q-AVC), Aortic valve closure-E (AVC-E), Q-Mitral valve
closure/Aortic valve closure-E (Q-MVC/AVC-E), left ventricle-deceleration time (LV-DT), peak
velocity-deceleration time (PV-DT) and A/E velocity time integral (A/E VTI) were evaluated.
Immediately after echocardiography all patients underwent left heart catheterization for LVEDP
measurement. The relation between different echocardiographic measurements and LVEDP,
obtained by cardiac catheterization, was evaluated.
RESULTS: In this study, 47 patients with ischemic heart disease with mean age (±SD) of
53 ± 13 were studied. There was a significant correlation between LVDEP and A/E VTI (r=0.44,
P = 0.001, and also between LVEDP and PV-DT in patients with A/E VTI ≥1.1(r = -0.58, P = 0.02).
There was a significant correlation between LVEDP and Q-MVC/AVC-E in patients with LVEDP
>18mmHg (r = 0.76, P= 0.03) and those with LVEDP ≤18 mmHg and A/E VTI < 1.1
(r = 0.37, P= 0.03). The correlation between LVEDP and A/E VTI was more significant in men,
in patients aged > 50 years with EF > 55%, without LVH, without MR and those with coronary
artery disease (P < 0.05).
CONCLUSION: Some echocardiographic indices such as A/E VTI, Q-MVC/AVC-E and PV-DT
are able to measure LVEDP especially in male patients aged > 50 years, without LVH, without
MR and those with coronary artery disease but it is necessary to determine specific conditions
and factors affecting these indices, by further studies.
Keywords: LVEDP, Coronary Artery Disease, Echocardiography.
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