The correlation between thrombolysis in myocardial infarction and angiographic scores in patients with ST-elevation myocardial infarction

Abstract

BACKGROUND: Myocardial infarction is a common and lethal disease, especially in the first
hours. Rapid and correct decision is essential to prioritize advanced therapies. This study
followed the accuracy of a scoring system for this triage. The aim was to assess the correlation
between thrombolysis in myocardial infarction risk scores and angiographic scores in patients
with ST elevation myocardial infarctio.
METHODS: In this cross-sectional, correlation study, 240 patients with ST elevation
myocardial infarction from coronary care units (CCUs) of 3 academic hospitals in Isfahan, Iran,
were evaluated. Thrombolysis in myocardial infarction risk score was calculated. All subjects
underwent angiography and were followed up for 2 months.
RESULTS: Mean age of patients was 60.02 ± 11.95 years old and 79 patients were female. The
correlation between thrombolysis in myocardial infarction risk and angiographic scores was
significant (P < 0.001). In addition, the correlations between ejection fraction and thrombolysis
in myocardial infarction risk score (P < 0.001), as well as angiographic score and age (P < 0.001)
were significant. There was no significant correlation between angiographic score and recurrent
angina (P = 0.143), rehospitalization (P = 0.524), and death (P = 0.179). Pearson's correlation
showed a significant relation between thrombolysis in myocardial infarction risk score and
angiographic score (P < 0.001; r = 0.556).
CONCLUSION: This study showed that thrombolysis in myocardial infarction risk score could
probably be used for evaluating the angiographic extent of coronary artery disease. If confirmed
by a prospective cohort study, simple clinical use of this score at bedside would make it a
method to stratify patients in high and low risk groups. Diagnostic and therapeutic strategies
would accordingly be catgorized.
Keywords: Thrombolysis in Myocardial Infarction Risk Score, Angiographic Score, ST Elevation
Myocardial Infarction, Ejection Fraction.