ARYA Atherosclerosis6320101222THE CORRELATION BETWEEN LIPID PROFILE AND STRESS LEVELS IN PART CENTRAL IRAN: ISFAHAN HEALTHY HEART PROGRAM217217ENMaryamShahnamHamidrezaRoohafzaPsychiatrist, Isfahan Cardiovascular Research Centre, Isfahan University of Medical Sciences, Isfahan, Iran.. roohafza@crc.mui.ac.irMasoumehSadeghiAliakbarTavassoliAhmadBahonarNizalSarrafzadegan20101220Abstract            Background: Previous studies suggest that mental status may influence serum lipid levels. This study was conducted on adult population living in rural and urban areas in Central Iran to assess the correlation between stress level and lipid profile disorders.Methods: Data was extracted from final evaluation of Isfahan Healthy Heart Program (IHHP) in 2008. Multistage and random cluster methods were used for sampling. The study population consisted of 9752 adults aged ≥19 years living in three districts namely Isfahan, Arak and Najaf Abad. Demographic data, age and sex were recorded. Blood samples were taken to determine the lipid levels including total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), low levels of high-density lipoprotein cholesterol (HDL-C) and triglycerides. Stress levels were assessed using the General Health Questionnaire. Logistic regression and chi-square tests were used for statistical analysis.Results: The odds ratios of high stress in individuals with high levels of TC, LDL-C and low levels of HDL-C compared to normal individuals after adjustment for age and sex were as follows respectively: 1.05 (1.02,1.15), 1.06 (1.02,1.18), 1.06 (1.01,1.17).Conclusion: Intervention activities towards reduction of stress levels at the community level may be useful as part of the strategy for cardiovascular disease prevention. Keywords: Cholesterol, Triglycerides, Stress, Questionnaire, Adult