ARYA Atherosclerosis6320101223WHAT EVERY CARDIOLOGIST SHOULD KNOW ABOUT H1N1?220220ENAllahyarGolabchiMD, Resident of Cardiology, Department of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.. golabchi@edc.mui.ac.irNizalSarrafzadegan20101223The world is witnessing ever fastest growing pandemic with high morbidity and mortality that excessive volume of airline travels spread influenza infection ; so physicians with various specialties should know and consider the impact of current pandemic on their daily practice. Among influenza A viruses that infect humans, an influenza A virus emerged that had shifted to H1N1. Primarily, the results of pandemic of H1N1 were in younger humans without preexisting immunity. Attack rates of swine influenza are relatively high but mortality is relatively low and mortality  rate is highest in the very young, the very old, and the immunosuppressed. In this new pandemic, there is not more evidence of the interface of H1N1 with chronic diseases; however, we expect that the Swine flu such as the previous influenza pandemics can change the course of many chronic diseases.In this review, we want to show the impacts of swine flu on cardiovascular system and diseaes. We will also discuss the importance of vaccination in chronic cardiovascular disease.